(2R)-2-[(tert-Butoxy)carbonylaMino]-3-[(2-nitrophenyl)aMino]propanoic acid - Names and Identifiers
(2R)-2-[(tert-Butoxy)carbonylaMino]-3-[(2-nitrophenyl)aMino]propanoic acid - Physico-chemical Properties
Molecular Formula | C14H19N3O6
|
Molar Mass | 325.32 |
Density | 1.335±0.06 g/cm3(Predicted) |
Boling Point | 562.1±50.0 °C(Predicted) |
pKa | 3.65±0.10(Predicted) |
(2R)-2-[(tert-Butoxy)carbonylaMino]-3-[(2-nitrophenyl)aMino]propanoic acid - Introduction
(R)-(-)-2-tert-butoxycarbonylamino-3-(2-nitrophenylamino) propionic acid (Boc-ANPAP) is an organic compound whose chemical formula is C14H20N4O6.
Nature:
Boc-ANPAP is a solid powder with low solubility. It is a chiral compound with one chiral center and therefore exists as stereoisomers. Its optical rotation is negative.
Use:
Boc-ANPAP are commonly used as chiral reagents or catalysts for the preparation of chiral compounds in organic synthesis. It can achieve chiral induction or chiral selection by reacting with other compounds, such as acetal ketal reaction, oxidation reaction and aryl carbon-hydrogen bond activation.
Preparation Method:
The synthesis of Boc-ANPAP is usually achieved by chemical synthesis. Specifically, the synthesis can be carried out by nitrating aniline, then aminating to obtain mixed amine, then reacting with (R)-2-tert-butoxycarbonyl-3-propionic acid, and finally refining, crystallization and other processes to obtain the target product.
Safety Information:
Boc-ANPAP safety information is limited, so strict protective measures should be taken during use and chemical safety procedures should be followed. It can be irritating to the human body, especially to the eyes and skin. In the event of exposure to the compound, immediately flush the area with plenty of water and seek medical attention if necessary. Avoid contact with oxidants, acids and high temperatures during storage.
Last Update:2024-04-10 22:29:15